antibody neutralization activity – Communicable Diseases Research

Effects of Spike Mutations in SARS-CoV-2 Variants of Concern on Human or Animal ACE2-Mediated Virus Entry and Neutralization

인간 또는 동물 ACE2 매개 바이러스 진입 및 중화에 대한 우려의 SARS-CoV-2 변이체에서 스파이크 돌연변이의 영향

Article

Published on 2022-06-292022-09-11
Journal: Microbiology Spectrum
[Category] COVID19(2023년), MERS, SARS, 변종, 진단,

Evaluation of Neutralizing Antibodies against SARS-CoV-2 Variants after Infection and Vaccination Using a Multiplexed Surrogate Virus Neutralization Test

다중 대리 바이러스 중화 테스트를 사용한 감염 및 예방 접종 후 SARS-CoV-2 변이체에 대한 중화 항체 평가

Article

Published on 2022-05-182022-09-11
Journal: Clinical Chemistry
[Category] COVID19(2023년), MERS, SARS, 변종, 진단,

[키워드] ACE2 angiotensin angiotensin converting enzyme Angiotensin converting enzyme-2 antibody Antibody neutralization antibody neutralization activity Antibody therapeutics approach B.1.1.7 B.1.351 binding Cohort cohorts Concordance COVID-19 COVID-19 pandemic COVID-19 patient Decline demonstrated determine diagnostics Effectiveness evaluated Evolution immune response inception individual inhibit measure Moderna mRNA vaccines mutated neutralization neutralization activity neutralization test neutralizing capacity Pfizer-BioNTech plaque reduction neutralization Plaque reduction neutralization test post infection PRNT Protective provide question reduced required SARS-CoV-2 SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV-2 virus serum significantly Spike protein surrogate surrogate virus neutralization test Surrogate virus neutralization test. sVNT Test Trimeric spike protein vaccinated individual vaccination Vaccine variants virus virus neutralization test wild type
[DOI] 10.1093/clinchem/hvab283 PMC 바로가기 [Article Type] Article

SARS-CoV-2 variants with reduced infectivity and varied sensitivity to the BNT162b2 vaccine are developed during the course of infection

감염성이 감소하고 BNT162B2 백신에 대한 감도가 다양한 SARS-COV-2 변이체가 감염 과정에서 개발됩니다.

Clinical Trial

Published on 2022-01-122022-08-13
Journal: PLoS Pathogens
[Category] Biochemistry, 변종, 임상, 치료기술, 치료법,

[키워드] addition Affect Analysis analyzed Anti-spike Antibody neutralization antibody neutralization activity Author BNT162b2 BNT162b2 vaccine circulating convalescent plasma Course COVID-19 vaccine COVID-19 vaccines demonstrated elicit employment Evolution Frequency highlight Host human host human population impair in-depth analysis increase in individual infected individual infected individuals Infection infectivity capacity intra-host SARS-CoV-2 variant intra-host SARS-CoV-2 variants Intra-host variant intra-host variants L1197I mutation landscape less low frequencies mRNA mRNA-based mutated mutated variant mutated variants N gene N genes natural infection neutralization Neutralizing antibodies nose-throat swab nose-throat swabs pandemic plasma plasma neutralization activity platform Point mutation potential circulating variants Protective Quasispecies quasispecy raised reduced respiratory Respiratory system S gene S2 subunit SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 intra-host variability SARS-CoV-2 intra-host variant SARS-CoV-2 intra-host variants SARS-CoV-2 mutagenesis SARS-CoV-2 variant SARS-CoV-2 variants sensitivity Sequencing Sequencing database Sequencing databases single-genome sequencing Spike protein Spike proteins spike variant Spread swab sample swab samples the SARS-CoV-2 the spike protein vaccinated individuals vaccination rate variant variants variants of concern
[DOI] 10.1371/journal.ppat.1010242 PMC 바로가기 [Article Type] Clinical Trial

A SARS-CoV-2 Label-Free Surrogate Virus Neutralization Test and a Longitudinal Study of Antibody Characteristics in COVID-19 Patients

SARS-CoV-2 표지 없는 대리 바이러스 중화 테스트 및 COVID-19 환자의 항체 특성에 대한 종단 연구

Article

Published on 2021-06-182022-09-12
Journal: Journal of Clinical Microbiology
[Category] MERS, SARS, 진단,

[키워드] ACE2 acute respiratory syndrome angiotensin-converting enzyme 2 antibody Antibody avidity antibody neutralization activity applicability binding ability Concentration coronavirus coronavirus disease COVID-19 Deterioration determine domain humoral IgG immunoassay include Increases individuals inhibitory concentration initial label-free technology Laboratory longitudinal longitudinal study molecular interaction neutralization Neutralizing neutralizing antibody Neutralizing antibody titer Patient platform post-symptom onset Postinfection RBD reduction in Research SARS-CoV-2 SARS-CoV-2 spike protein serum serum sample surrogate surrogate neutralization virus test. symptom onset Test Variability virus virus neutralization test
[DOI] 10.1128/JCM.00193-21 PMC 바로가기 [Article Type] Article